The Pain Research Centre (PaRC)
The Royal London and St Bartholomew's Hospital, London
Ongoing Studies

Multifidus Stimulation Study -
MUST study
A prospective single arm pilot study investigating the brain and multifidus muscle response through Positron Emission Tomography (PET) in patients with low back pain receiving Reactiv8 stimulation.
Radiofrequency Denervation for Chronic and Moderate to Severe Low Back Pain - RADICAL Study
A double blind randomised control trial evaluating the effectiveness and cost-effectiveness of radiofrequency denervation in patients with moderate to severe chronic localised lower back pain.


RELIEF 2 Study
A prospective global multi-centre registry to evaluate longterm outcome data on patients with spinal cord stimulation. The main purpose of the study is to compile characteristics of real-world clinical outcomes for Boston Scientific neurostimulation systems for pain in routine clinical practice and to also evaluate the economic value and technical performance these neurostimulation systems.
Central Sensitisation Response following Occipital Nerve Stimulation
A prospective case study investigating the efficacy of quantitative sensory testing in detecting changes in pain in chronic migraine patients being treated with occipital nerve stimulation.


PRO (Patient Retrospective Outcomes) Study
A retrospective global multi-centre data review using
de-identified patient records to characterise real-world clinical outcomes with the use of Boston Scientific or acquired systems for treatment of chronic pain over 15 years.